Here's a reassuring analysis from Dan Primack at Fortune. An excerpt:
The truth is that the Twinkies brand still has value, and will be acquired. Same for Ding Dongs. And (probably) Wonder Bread. America may be undergoing major demographic shifts, but empty calories cut across age, gender and ethnicity. If the next generation's Twinkies don't have "Hostess" stamped on them, so be it. I'm not even certain the ironic heart carries much weight in our post-Saturday morning cartoon world.