If your job hunt consists of posting a resume on monster.com, this CareerJournal article will give you some better strategies, some of which may be surprising, such as it makes sense to apply for jobs that have been posted for a while.
Quality (in resume and letter) + Quantity (in number of contacts) + Interview prep + Interview performance = Eventual job. There are exceptions, but this is the traditional approach.
It can, however, be shortened to:
Quality (in resume) + Quality (of contacts) = Fast job offer.