Wonder Pill?

Writing in Wired, Brandon Keim looks at caloric restriction in one pill:

Resveratrol didn't extend the lives of normal mice, but it did protect them from the ravages of time. The rodents had stronger hearts, clearer eyes, more limber muscles and firmer bones. Closer analysis revealed the same cell-level changes produced by caloric restriction, an extreme form of dieting that consistently lengthens the lives of lab animals but is impractical, if not dangerous, for people.

"For the first time, we can mimic caloric restriction in an otherwise healthy animal," said study co-author David Sinclair, a Harvard University biologist and co-founder of Sirtris Pharmaceuticals. "That's been the goal of the field for decades. We didn't know it was possible to let an animal eat whatever it wants, but still get the benefits. We now have evidence."