Anderson Layman's Blog has a post with some great opening lines from books. I'd add this first paragraph from Godric by Frederick Buechner:
Five friends I had, and two of them snakes. Tune and Fairweather they were, thick round as a man's arm, my bedmates and playfellows, keepers of my skimped hearth and hermit's heart till in a grim pet I bade them go that day and nevermore to come again, nevermore to hiss their snakelove when they saw me drawing near or coil themselves for warmth about my shaggy legs. They went. They never came again.